Craving a flavorful and comforting meal? Look no further than this Creamy Cajun Shrimp and Chicken Pasta! Packed with bold Cajun spices and enveloped in a rich, creamy sauce, this dish is the perfect blend of Southern soul and Italian comfort. It’s ideal for a cozy weeknight dinner or a lively get-together with friends. Plus, it’s surprisingly easy to make with fresh ingredients that will delight your taste buds!

Ingredients:
Serves 4-6
- Protein:
- 300g (10 oz) chicken breast, sliced into strips
- 250g (8 oz) shrimp (peeled and deveined)
- Cajun Seasoning:
- Use 2 tablespoons of Cajun spice mix. You can also make your own. Combine paprika, garlic powder, onion powder, thyme, black pepper, cayenne, and oregano
- Pasta:
- 400g (14 oz) pasta (penne, fettuccine, or linguine work great)
- For the creamy sauce:
- 2 tablespoons butter
- 3 cloves garlic, minced
- 1 small onion, finely diced
- 1 red bell pepper, diced
- 250ml (1 cup) heavy cream
- 100g (½ cup) grated Parmesan cheese
- Extras:
- Olive oil for cooking
- Salt and pepper to taste
- Fresh parsley, chopped (for garnish)

Instructions:
- Prepare the proteins:
- Season the chicken with half of the Cajun spice mix, a drizzle of olive oil, salt, and pepper.
- Heat a tablespoon of olive oil in a large non-stick skillet over medium-high heat.
- Sauté the chicken strips for 5-7 minutes until golden brown. Remove from the skillet and set aside.
- In the same skillet, add a little butter and cook the shrimp with the remaining Cajun seasoning for about 2-3 minutes on each side. Set aside.
- Make the sauce:
- In the same skillet, melt the remaining butter and add the minced garlic. Sauté for about 1 minute.
- Add the diced onion and red bell pepper. Cook for 3-4 minutes until softened.
- Pour in the heavy cream and bring to a gentle simmer. Stir in the grated Parmesan cheese until the sauce is smooth and creamy.
- Cook the pasta:
- Meanwhile, cook the pasta in a pot of salted boiling water according to the package instructions.
- Drain the pasta when al dente and add it directly to the skillet with the sauce. Stir to combine.
- Combine everything:
- Return the chicken and shrimp to the skillet with the pasta and sauce. Gently toss to distribute the flavors evenly.
- Let it rest over low heat for 2-3 minutes to allow the ingredients to meld together.
- Serve:
- Garnish with freshly chopped parsley and an extra sprinkle of Parmesan, if desired.
- Serve hot, alongside garlic bread or a fresh seasonal salad.
Nutritional Information: (per serving, approximately)
- Calories: 620 kcal
- Protein: 42g
- Carbohydrates: 58g
- Fat: 25g
- Fiber: 4g
- Sodium: 950mg
Tips for Fresh Ingredients and Variations:
- Shrimp: Choose high-quality fresh or frozen shrimp. Argentine pink shrimp have a particularly rich flavor.
- Chicken: Organic or free-range chicken breast offers a more tender and flavorful bite.
- Vegetables: Add mushrooms, zucchini, or spinach to the sauce for an extra boost of veggies.
- Pasta: Opt for whole wheat or legume-based pasta for a healthier alternative.
Recipe Variations:
- Vegetarian: Replace the chicken and shrimp with smoked tofu and Portobello mushrooms.
- Dairy-free: Use coconut or soy cream and omit the Parmesan cheese.
- Spicy: Add an extra dash of cayenne pepper for a bolder heat!
Recommended Pairings:
- Wine: A crisp Sauvignon Blanc or Pinot Grigio pairs beautifully with the dish’s rich, spicy flavors.
- Side Dishes:
- Garlic bread
- Green salad with lemon vinaigrette
- Grilled vegetables like asparagus or zucchini

Conclusion:
This Creamy Cajun Shrimp and Chicken Pasta is a perfect explosion of flavors and textures, with the creamy sauce balancing the bold Cajun spices. It’s a versatile dish you can easily adapt to your tastes or dietary needs. Try this recipe and impress your family or guests with a meal that tastes like it came straight from a restaurant!
FAQs for Creamy Cajun Shrimp and Chicken Pasta Recipe
1. Can I use store-bought Cajun seasoning?
Yes, store-bought Cajun seasoning works perfectly for this recipe. If you prefer, you can also make your own by combining paprika, garlic powder, onion powder, thyme, black pepper, cayenne pepper, and oregano.
2. What type of pasta is best for this dish?
You can use a variety of pasta types such as penne, fettuccine, or linguine. For a healthier option, you can use whole wheat or gluten-free pasta.
3. How do I prevent the shrimp from becoming rubbery?
Shrimp can become rubbery if overcooked. Sauté them on medium-high heat for 2-3 minutes per side until they turn pink and opaque, then remove them from the heat.
4. Can I substitute the chicken and shrimp with other proteins?
Absolutely! You can use turkey, sausage, or even salmon. For a vegetarian option, try smoked tofu or mushrooms.
5. How can I make the dish spicier?
For extra heat, add more cayenne pepper or a pinch of red pepper flakes to the Cajun seasoning or the creamy sauce.
6. Can I make the sauce without heavy cream?
Yes! You can use half-and-half, coconut milk, or a plant-based cream alternative if you’re avoiding dairy. Keep in mind that this may slightly change the taste and texture of the sauce.
7. How do I store and reheat leftovers?
Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat gently in a skillet over low heat with a splash of cream or water to loosen the sauce.
8. Can I make this dish ahead of time?
You can prepare the sauce, chicken, and shrimp ahead of time, but it’s best to cook the pasta fresh when you’re ready to serve. This helps maintain the best texture for the dish.
9. What are good side dishes to serve with this pasta?
Great options include garlic bread, a simple green salad with vinaigrette, or grilled vegetables like asparagus or zucchini.
10. Is this dish kid-friendly?
Yes! If your kids are sensitive to spice, you can reduce the amount of Cajun seasoning or use a milder version without cayenne pepper.
- Homemade Cajun Seasoning Recipe – Learn how to make your own Cajun seasoning.
AllRecipes – Cajun Seasoning Recipe - Choosing the Freshest Shrimp – Tips on how to select high-quality fresh or frozen shrimp.
Seafood Nutrition Partnership – Shrimp Selection Tips - Benefits of Whole Wheat Pasta – Discover why whole wheat pasta is a healthier option.
Healthline – Benefits of Whole Wheat Pasta - How to Cook Perfect Pasta – Avoid common mistakes and learn to cook pasta al dente.
The Kitchn – How to Cook Pasta Perfectly - Creamy Sauce Tips – Techniques for making a smooth, lump-free creamy pasta sauce.
Serious Eats – How to Make Creamy Pasta Sauce - Health Benefits of Lean Chicken Breast – Explore why chicken breast is a great source of lean protein.
Mayo Clinic – Chicken Nutrition and Benefits - How to Pair Wine with Spicy Foods – Find out the best wines to pair with Cajun-inspired dishes.
Wine Enthusiast – Wine Pairing with Spicy Food - Guide to Fresh Herbs – Learn how to use and store fresh herbs like parsley to enhance your cooking.
Bon Appétit – Fresh Herb Guide - How to Make Garlic Bread – A quick and easy recipe to create the perfect garlic bread for pasta dishes.
Food Network – Garlic Bread Recipe - Cajun Cuisine History – Discover the origins and rich history of Cajun cuisine.
National Geographic – History of Cajun Cuisine